Outsmart the market with Smart Portfolio analytical tools powered by TipRanks. The FDA has imposed a clinical hold on this gene therapy candidate that is being evaluated for a condition called phenylketonuria. Please disable your ad-blocker and refresh. Click on an acquiring company to pull up more information, and scroll to the bottom of the page to read how this information was collected and organized. The Motley Fool owns shares of and recommends CRISPR Therapeutics and Vertex Pharmaceuticals. ET, 5 Reasons to Buy Vertex Pharmaceuticals Now, 3 Biopharma Stocks That Could Help Make You a Fortune. Additionally, Dan is a Scientist and inventor. Price as of January 17, 2023, 4:00 p.m. There were a few, but not as many. The quest behind the drive is to fill potential gaps in the pipeline. While oncology and immuno-oncology are the key areas of focus, treatments for rare diseases and gene-editing companies also promise potential, making them lucrative investment areas. This therapeutic has been licensed to Swiss pharma giant Novartis. The company did have its fair share of troubles when the FDA rejected its application for Ocaliva in NASH, and late last year the company withdrew its application filed with the European Medicines Agency for the same. The Company submitted a Marketing Authorization Application to the. All rights reserved. A report from industry analyst IQVIA suggests that "significant deal activity, both in terms of volume and value, will continue to be seen in oncology, with next-generation biological therapies such as neoantigen-directed approaches likely to attract considerable big pharma interest". One of leaders in this field is CRISPR Therapeutics, a Cambridge (MA)-based biopharmaceutical company focused on the discovery and development of transformative genetic medicines for serious human diseases such as hemoglobinopathies, diabetes, or cancer. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. This package might sound almost too good for some of the big pharmaceutical companies. Moreover, companies investing in mRNA technology are gaining a lot of attention, given the success of the technology in the development of COVID-19 vaccines. Powered by Madgex Job Board Software. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Dealmaking is essential to the business of drug development. Financial Market Data powered by FinancialContent Services, Inc. All rights reserved. However, given the commercial success of Jakafi and its enterprise market value, Incyte still remains an attractive takeover target, according to some analysts. The uptake of all these products has been good. Abbott Laboratories bought out Solvay Pharmaceuticals for $6.1B. Invest better with The Motley Fool. Sold CoTherix, Inc. to Actelion Pharmaceuticals Ltd.: Mr. Rosen served on the Board of Directors of CoTherix, Inc. Actelion Pharmaceuticals bought out CoTherix for $420M. The management team has been involved in thirteen different acquisitions. The number of done deals dropped to 92 from 101 in 2020 and 111 in 2019. The company has three marketed products and boasts of a vibrant pipeline, with a host of investigational therapeutics. CRISPR/Cas9 is one of the hottest technologies of todays biomedical research. Gilead Sciences (GILD -1.00%) also has not been shy about making smaller deals. Biotech Merger And Acquisition Rumors And News October 3rd, 2013 by Scott Matusow. I could see a big pharma seeing the cash flows from the cystic fibrosis drugs justifying the price, and then that leaves the call option on all of its pipelines, as well as the drugs that Vertex has in-licensed. Making the world smarter, happier, and richer. And how much are they willing to spend? That remains to be seen. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. Shockwave Medical bolsters medical device portfolio with acquisition of Neovasc. The other candidates in the pipeline include CTX110, CTX120 and CTC130, all for immuno-oncology indications. quotes delayed at least 15 minutes, all others at least 20 minutes. Biotech companies have had an easy time raising huge sums of money from private investors and, until recently, the public markets. But the way I see it, there's plenty of biotechs in the sea to reinvest those profits. 10. While M&A was plentiful in 2018 and 2019, and even held up during a year gripped by the coronavirus pandemic, 2021 was much quieter. Big pharma companies will be keen on picking up biotech stocks for deal sizes in the $5 billion to $15 billion range. Leading gene-editing biotechs CRISPR Therapeutics and Intellia are likely to be acquired at some point. 8. Clovis leading drug Rubraca (rucaparib), a poly (ADP-ribose) polymerase (PARP) inhibitor, has been approved by the FDA for the treatment of ovarian and prostate cancer. Politics. The rumors on Obagi turned out to be correct, as the company was sold last. If there's anything we've missed, or any additional information you'd like to see, please reach out and let us know. This management team has time and time again sold companies for nice premiums. However, there is no way to know for sure since I'm not an insider and have no inside information. Capsa Healthcare, a leading innovator in healthcare delivery solutions for hospitals, long-term care, and retail pharmacy providers, announced the acquisition of Tryten Technologies Inc., a designer and manufacturer of lightweight, easy to maneuver mobile cart solutions. If the letter of intent to acquire your company has been signed, you might be asking what happens next. If there's a company that wants to get a lot of external deals all wrapped up in one little bundle, I think that Vertex would be a good acquisition target. 1. I'm thinking Intellia (NASDAQ: NTLA) potentially being acquired by Regeneron (NASDAQ: REGN), and CRISPR Therapeutics (NASDAQ: CRSP) potentially being acquired by Vertex Pharmaceuticals. And there are often rumors of other deals that never materialize. At the time, I was contacted by a former investment banker who stated to me that he heard there would be an eventual deal with Antares and that it was "a done deal, but the deal has not been done." I think the CRISPR gene-editing companies are probably likely to get snatched up at some point, probably by their partners, especially as they've reached proof-of-concept. The company has already seven products on the market. In the 3rd quarter call, Jack Howarth stated that Antares approached Pfizer looking to collaborate with them. *Stock Advisor returns as of January 10, 2022. It is focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. With $94.6 million in cash and cash equivalents as of June 30, the American company is facing a very delicate cash situation. Well, first, I am a shareholder of both Vertex and Bristol-Myers Squibb, so I like your ideas there. Markets. Acquisition rumors have swirled around specialty biotech BioMarin Pharmaceutical (NASDAQ: BMRN) for years now.In fact, Genetic Engineering & Biotechnology News has had it on its takeover target . M&A has always taken center stage in the biotech industry as leading pharma/biotech companies constantly eye lucrative acquisitions to diversify their revenue base in the face of dwindling sales of high-profile drugs. Speights: Now, Brian, I'm going to agree with you on every point you just made. The Food and Drug administration (FDA) approved its fourth RNAi therapeutic product Leqvio in December 2021 for lowering LDL-cholesterol, aka bad cholesterol. I'm thinking Intellia (NTLA -1.57%) potentially being acquired by Regeneron (REGN 0.83%), and CRISPR Therapeutics (CRSP 3.66%) potentially being acquired by Vertex Pharmaceuticals (VRTX 3.67%). It expects to grow its revenues by 14% in the next fiscal year. Ionis has clinical study collaborations and strategic partnerships with the high-and-mighty of the industry, including Roche, Biogen (NASDAQ:BIIB) and AstraZeneca (NASDAQ:AZN). Luke Lango will reveal how you could start collecting cash payouts like $4,600 in 48 days or $12,000 in 21 days, without touching risky options or any other confusing investments. Vertex should consider buying CRISPR Therapeutics, with which it already is partnering. The rumors died down after Novartis announced in early January another collaboration with Alnylam for developing targeted therapies to restore liver function. Please. Together with bluebird bio, CRISPR Therapeutics competes for approval of the first genetic medicine to treat beta thalassemia and sickle cell disease, two inherited blood disorders affecting millions of people worldwide. Copy and paste multiple symbols separated by spaces. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. Vascepa secured its first FDA approval in 2012 for treating patients with very high triglyceride levels and as recently as yesterday (Dec.14) was approved for wider use, i.e., to help address residual cardiovascular risk beyond cholesterol management. He utilizes a combination of technical analysis, deep scientific research, and macro views to generate alpha for the team. It is running mid-stage clinical trials of the drug, in combination with bezafibrate, in PBC, late-stage studies in non-alcoholic steatohepatitis (NASH) and a mid-stage study in biliary atresia. This cannot be the undisclosed product for which Antares and Pfizer are in a partnership for. BMRN briefly touched $100.13 on February 5, 2019. Places you can follow Scott are: www.stockmatusow.com www.twitter.com/StockMatusow @StockMatusow http://www.facebook.com/TheScottMatusowShow Places to follow Dan are: https://twitter.com/biosleuth. The surge in transactions in the pharmaceutical industry saw 16 deals during 2022 - seemingly the largest number in a decade, worth several billion dollars in value. Clovis Oncology shares have gained 270% since November, and trade around $13. All rights reserved. Below we discuss companies that have promising drugs/candidates in the pipeline and could be potential takeover targets: BioMarin BMRN has been on the takeover radar for quite some time now. Total consideration can reflect both cash and equity offered upfront in exchange for the acquired companys shares, but deals in which the upfront payment was not specified, or was less than $50 million, were not included. Therefore, there are always lots of buyout rumors in the news about potential biotech takeover targets. I didn't give the rumor much weight until Antares announced a deal with Pfizer, and then hired former King Pharma insider, Jack Howarth. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Lynparza is co-developed by AstraZeneca and Merck, while Zejula, which is from the stable of Tesaro, is now under the aegis of GlaxoSmithKline, following the former's acquisition by the British drugmaker. If all goes well as planned, the Company will have another drug on the market - Pemigatinib - as a treatment for Cholangiocarcinoma, a rare cancer that forms in the bile duct. The biopharma sector could be in for reversal after a not-so-enterprising performance in 2021. Are you interested in learning more about biotech stocks with exceptional future perspectives and some of the hottest takeover targets of the industry? One of the catalysts that could work in its favor is deal optimism. The companys CRISPR/Cas9 platform uses gene editing technology that allows precise, directed changes to genomic DNA. Clovis Oncology is a commercial-stage biotechnology company whose lead drug is Rubraca, indicated for ovarian cancer. These apart, updates on vaccines for COVID-19 continue to grab the limelight as the world at large is in dire need of the same to combat the . Subsequent letters and public pressure from Voce eventually lead to the Obagi Acquisition. Pharma giant Pfizer recently announced that it will acquire Arena Pharmaceuticals for $100 per share or a total equity value of approximately $6.7 billion to further expand its portfolio. Ra Medical Systems (NYSE American: RMED) announces a realignment of its board of directors in conjunction with the recently announced merger with Catheter Precision, Inc. David Jenkins has joined the board as Executive Chairman and James Caruso has been named director. Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech partners. In January of this year, rumors began to circulate that Pfizer (PFE) might be interested in acquiring Amarin. Always do your own due diligence before buying and selling any stock, and/or consult with a licensed financial adviser. BioMarin Pharmaceuticals is an American biotechnology company headquartered in San Rafael, California, focusing on the development and commercialization of innovative biopharmaceuticals for rare genetic diseases. BioMarins development pipeline includes hemophilia A gene therapy candidate valoctocogene roxaparvovec. Per rumors, South-Korean conglomerate Samsung Group is reportedly in talks to acquire Biogen BIIB. Bayer announced the acquisition of the global strategic imaging AI platform and solutions provider Blackford Analysis Ltd. Freight. Learn More. BioNTech Strengthens Its Artificial Intelligence With Acquisition Of British . They just revealed what they believe are the ten best stocks for investors to buy right now and Vertex Pharmaceuticals wasn't one of them! Cash position at the end of the fiscal year was at $1.52 billion. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. The Cambridge, Massachusetts-based biopharma has three commercial products on the market. BioMarin(NASDAQ:BMRN) focuses on gene therapies, one of the most recent treatment paradigms that promise huge scope for treating serious and life-threatening genetic disorders. Alnylam Pharmaceuticals ALNY is another company that should attract eyeballs. Alexion Pharmaceuticals. The companys drug Ocaliva has been approved for primary biliary cholangitis. Learn More. AcelRx (ACRX). Targeted indications include cardio-renal, metabolic, neurological, infectious diseases, cancer, ophthalmology, pulmonary & allergy and hematology. Oct 2007 Alphapharma hires Howarth VP of Investor Relations, June 2009 King hires Howarth VP of Investor Relations, Feb 2012 Antares hires Howarth VP of Investor Relations. 2023 InvestorPlace Media, LLC. I own Vertex so I certainly don't want Vertex overpaying for CRISPR Therapeutics. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. That funding can make them less receptive to a buyout and force would-be acquirers to offer more to lock down deals. An early-stage asset, codenamed BMN 307, is mired in trouble. Keith Speights owns Bristol Myers Squibb and Vertex Pharmaceuticals. The global strategic imaging AI platform and solutions provider Blackford analysis Ltd. Freight out Solvay Pharmaceuticals for $ 6.1B you. The sea to reinvest those profits the pipeline Alnylam Pharmaceuticals ALNY is another company that should attract.. Of the industry Vertex should consider buying CRISPR Therapeutics and Vertex Pharmaceuticals dropped to from. The company submitted a Marketing Authorization Application to the Marketing Authorization Application to the Obagi Acquisition happens next learning... Reasons to Buy Vertex Pharmaceuticals rumors of other deals that never materialize been for. To Swiss pharma giant Novartis is a commercial-stage biotechnology company whose lead drug Rubraca! 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